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The Correlation of Endothelium Cell Density and Quality of the Cornea after Penetrating Keratoplasty

The Correlation of Endothelium Cell Density and Quality of the Cornea after Penetrating Keratoplasty

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20170316001
Enrollment
Unknown
Registered
2017-03-16
Start date
2010-01-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The corneal endothelium is a key to maintain transparency and clarity of cornea by pump&#45

Interventions

PKP,Control
patients after penetrating keratoplasty,patients non&#45

Sponsors

Faculty of Medicine Siriraj Hospital, Mahidol University
Lead Sponsor
Department of Ophthalmology&#44
Collaborator
Faculty of Medicine Siriraj Hospital&#44
Collaborator
Mahidol University
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: in PKP : patients with age more than 18 years old who performed PKP and had graft clear, no irregular surface and scare.They could measure endothelial cell density, no active sign of graft rejection and inflammation at the time of examination In none -keratoplasty : patients who had never done PKP who had data of endothelial cell density and pachymetry

Exclusion criteria

Exclusion criteria: for PKP group are included patient with younger than 18 years old, with one or more sign of graft rejection, irregular surface, opacity of the graft that obscured endothelial cell density counting, and corneal scar For none - PKP group were patients under 18 years old, patients with corneal guttata, irregular surface, corneal opacity or scar, patient who had or history of corneal infection, uveitis, immunocompromised patient, patient who had the endothelial examination were not clear enough to count endothelial cell density.

Design outcomes

Primary

MeasureTime frame
endothelial cell density N/A evaluate endothelial cell density in patients after PKP versus non-PKP

Secondary

MeasureTime frame
corneal thickness N/A corneal thickness in patients after PKP versus non-PKP

Contacts

Public ContactPinnita Prabhasawat

Department of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol University

pinnita.t@gmail.com+6624198037

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026