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Dynamic arterial elastance for predicting mean arterial pressure responsiveness after fluid challenges in acute respiratory distress syndrome patients

Dynamic arterial elastance for predicting mean arterial pressure responsiveness after fluid challenges in acute respiratory distress syndrome patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20170306001
Enrollment
Unknown
Registered
2017-03-06
Start date
2017-03-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute respiratory distress syndrome with acute circulatory failure Dynamic arterial elastance Acute respiratory distress syndrome (ARDS) Mean arterial pressure responsiveness Fluid challenges

Interventions

The patients who are diagnosed acute respiratory distress syndrome (ARDS) indicated by PaO2/FiO2 ratio < 300. The ventilator setting in these patients should protect the lungs with tidal volume < 8 m
Diagnostic
Acute Respiratory Distress Syndrome

Sponsors

Faculty of Medicine Ramathibodi Hospital&#44; Mahidol University
Lead Sponsor
Faculty of Medicine Ramathibodi Hospital&#44
Collaborator
Mahidol University
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: &#45; Age >= 18 years &#45; ARDS; P/F ratio<300 &#45; On mechanical ventilator with tidal volume < 8 ml/kg (predicted body weight) &#45; Acute circulatory failure &#45; Fluid responsiveness

Exclusion criteria

Exclusion criteria: &#45; Arrhythmias &#45; low LVEF &#45; On Inotropic drugs &#45; Abdominal hypertension &#45; HR: RR<3.6

Design outcomes

Primary

MeasureTime frame
Dynamic arterial elastance N/A Ratio of pulse pressure variation to stoke volume variation—

Secondary

MeasureTime frame
Predictive value N/A Cut point&#44; sensitivity&#44; specificity—

Countries

Thailand

Contacts

Public ContactPunchika Luetrakool

Department of Anesthesiology&#44; Faculty of Medicine Ramathibodi Hospital&#44; Mahidol University

punchi0906@gmail.com(66)841654482

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026