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Comparison of changes in ferritin and hs-CRP serum level in medical and surgical treatment of nasal polyps: randomized clinical trial

Comparison of changes in ferritin and hs-CRP serum level in medical and surgical treatment of nasal polyps: randomized clinical trial

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20170220001
Enrollment
Unknown
Registered
2017-02-20
Start date
2017-01-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sinonasal polyposis (SNP) inflammatory disease of the nasal mucosa hs&#45

Interventions

the patient who were treated with medical therapy independently using nasal spray of fluticasone and trained nasal irrigation with sodium chloride 0.9% 3 times a day. ,was treated with surgical metho
medical therapy,surgical therapy

Sponsors

Shahid Sadoughi University of Medical Sciences
Lead Sponsor
Shahid Sadoughi University of Medical Sciences
Collaborator

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patient who have not treated sinonasal polyposis, aged between 20 to 60 years and lund-macky score upper than 11 was included in this study. The lund-mackay scoring system which is the most popular system to evaluate the Computed tomography in sinus disease was used to evaluate the patients for the procedures they needed. In this scoring system a score of 0-1 or 2 were given to patient with normal, partial opacification, and total opacification respectively for each of this subsites: 1) anterior ethmoid 2) posterior ethmoid 3) frontal 4) maxillary and 5) sphenoid sinus on each side and for patent or obstructed osteomatal cavity in each side would give a 0 or 2 respectively. In this scoring system the maximum score were 12 and 24 for both sides. We assumed patients in two classes based on lund-mackay scoring, first group; mild (0-11), second group; severe (12-24), and the patient who were in class 2 can be included in our study.

Exclusion criteria

Exclusion criteria: We excluded patients with acute and chronic inflammation such as malignancy and rheumatism disease, infectious conditions, history of sinonasal Endoscopic surgery, using anti inflammation drugs, patients with anemia and received iron or blood products 1 month before study and incident of above conditions during one month follow up of our patients.

Design outcomes

Primary

MeasureTime frame
hs-CRP 24 hoour and 30 days after start ng/ml

Secondary

MeasureTime frame
serum ferritin 24 hoour and 30 days after start mg/L

Countries

iran

Contacts

Public Contactpouria yazdian

student, faculty of medicine

pouria_yazdian_a@yahoo.com0989385101025

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026