Obese children and adolescents with obstructive sleep apnea syndrome obstructive sleep apnea syndrome apnea hypopnea index
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Boy or girl aged 7-18 years old who have confirmed of OSAS (AHI > 1 or ODI > 1 or SaO2nadir < 92%) by using an overnight polosomnography (PSG) (3, 11). 2.Subjects who defined as overweight or obese individual, according to the criteria of the International Obesity Task Force (IOTF) (61).
Exclusion criteria
Exclusion criteria: 1) Subjects who had received other treatments that would influence study results e.g. CPAP therapy, medicines involved in weight control, behavioral modification and the other exercise program 2) Subjects who had any existing contraindications for exercise testing according to ACSM’s guideline 3) Subjects who had medical conditions that would affect study results i.e., symptomatic cardiac disease, hypertension (HT), diabetes mellitus (DM), any neurological deficits (i.e., dementia and poor mental status) and orthopedic problems that limit ability to ambulation or walking and 4) Subjects who had any implanted metal accessories. In addition, participant’s data would not be summarized if they demonstrate any of the following criteria; 1) Participants who had exercise adherence rate lesser than 85 percent of total exercise session (20/24 sessions) 2) Participants who were not willing to continue the program of the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sleep variable (Apnea Hypopnea Index, oxygen desatu) and vascular function (Flow Mediated Dilation) at baseline, after 8 weeks, and 8 week follow-up Sleep variables: Using polysomnography and PSQ questionnaire , vascular function: Ultrosonography,Sleep variable (oxygen desaturation index, SaO2nadir, MeanSaO2) at base ine, after 9 weeks, and after 17 weeks Portable Polysomnography | — |
Secondary
| Measure | Time frame |
|---|---|
| other sleep variables (SRBD scake), NO, body composition, BP at baseline, after 8 weeks, and 8 week follow-up Using polysomnography , blood sample,mechanical beam medical scale,sphygmomanometer | — |
Countries
Thailand
Contacts
Chiang Mai University