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The Effects of High Intensity Interval Training Combined with Resistance Training in Obese Children with Obstructive Sleep Apnea Syndrome

The Effects of High Intensity Interval Training Combined with Resistance Training on Sleep Breathing Variables and Vascular Function in Children and Adolescents with Obstructive Sleep Apnea Syndrome

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20170209001
Enrollment
42
Registered
2017-02-09
Start date
2017-03-10
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obese children and adolescents with obstructive sleep apnea syndrome obstructive sleep apnea syndrome apnea hypopnea index

Interventions

A total 17 weeks of exercise intervention is prescribed&#44
consisting of 1&#45
wk preparation phase&#44
wk training phrase and 2&#45
months follow&#45
up phase. In a preparation phase&#44
participants are first familiarized with equipments and exercise protocol one week before HIIT program beginning. They are asked to perform aerobic exercise program at moderated intensity (40&#45
60%HRR) combined with resistance training at 40% 1 repetition maximum (RM) for 3 days. After that&#44
wk program of HIIT combined with resistance exercise will be done three times per week&#44
totally 44 minutes a sessions. Five minutes of warm up period including active stretching exercise which involve in three parts of upper extremities&#44
lower extremities and trunk will be conducted. Each pose of active stretching exercise will be held 20 seconds and repeated 2 times. After that&#44
active large muscle exercise comprises of walking on treadmill or leg ergometer cycling will be carried out at a heart rate corresponding to 60%HRR)&#44
separated with recovery period at moderate intensity (40&#45
50%HRR). Subjects are instructed to exercise four&#45
3 minute at high intensity (>60%HRR) with&#45
3 minute active recovery period at 40&#45
50%HRR throughout first 8 weeks and last 8 weeks of the intervention. During the first 8 weeks of intervention&#44
the HRR will be re&#45

Sponsors

Graduate student of Chiang Mai University
Lead Sponsor
Faculty of Associated Medical Science
Collaborator

Eligibility

Sex/Gender
All
Age
7 Years to 18 Years

Inclusion criteria

Inclusion criteria: 1.Boy or girl aged 7&#45;18 years old who have confirmed of OSAS (AHI > 1 or ODI > 1 or SaO2nadir < 92%) by using an overnight polosomnography (PSG) (3&#44; 11). 2.Subjects who defined as overweight or obese individual&#44; according to the criteria of the International Obesity Task Force (IOTF) (61).

Exclusion criteria

Exclusion criteria: 1) Subjects who had received other treatments that would influence study results e.g. CPAP therapy&#44; medicines involved in weight control&#44; behavioral modification and the other exercise program 2) Subjects who had any existing contraindications for exercise testing according to ACSM’s guideline 3) Subjects who had medical conditions that would affect study results i.e.&#44; symptomatic cardiac disease&#44; hypertension (HT)&#44; diabetes mellitus (DM)&#44; any neurological deficits (i.e.&#44; dementia and poor mental status) and orthopedic problems that limit ability to ambulation or walking and 4) Subjects who had any implanted metal accessories. In addition&#44; participant’s data would not be summarized if they demonstrate any of the following criteria; 1) Participants who had exercise adherence rate lesser than 85 percent of total exercise session (20/24 sessions) 2) Participants who were not willing to continue the program of the study.

Design outcomes

Primary

MeasureTime frame
Sleep variable (Apnea Hypopnea Index&#44; oxygen desatu) and vascular function (Flow Mediated Dilation) at baseline&#44; after 8 weeks&#44; and 8 week follow&#45;up Sleep variables: Using polysomnography and PSQ questionnaire &#44; vascular function: Ultrosonography,Sleep variable (oxygen desaturation index&#44; SaO2nadir&#44; MeanSaO2) at base ine&#44; after 9 weeks&#44; and after 17 weeks Portable Polysomnography

Secondary

MeasureTime frame
other sleep variables (SRBD scake)&#44; NO&#44; body composition&#44; BP at baseline&#44; after 8 weeks&#44; and 8 week follow&#45;up Using polysomnography &#44; blood sample&#44;mechanical beam medical scale&#44;sphygmomanometer

Countries

Thailand

Contacts

Public ContactKhomkrip Longlalerng

Chiang Mai University

khomkrip.lo@wu.ac.th0812706355

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026