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Genicular nerve bipolar radiofrequency ablation for chronic osteoarthritis knee pain: A double-blind randomized controlled trial

Genicular nerve bipolar radiofrequency ablation for chronic osteoarthritis knee pain: A double-blind randomized controlled trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20170130003
Enrollment
64
Registered
2017-01-30
Start date
2017-03-15
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic knee osteoarthritis pain and response for treatment (Genicular nerve bipolar radiofrequency ablation VS dexamethasone injection) Chronic knee osteoarthritis pain, genicular nerve, radiofrequency ablation, genicular bipolar radiofrequency, knee pain, knee arthritis

Interventions

Skin and soft tissues will be anesthetized with 1 mL of 1% lidocaine. •Bipolar radiofrequency ablation of genicular nerves With the same position as diagnostic block and strictly sterile preparation
Geniculate bipolar RF Group,Sham Group

Sponsors

None listed

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Age 18 - 85 years and persistent knee pain > 6 months 2. Diagnosis of radiologically verified Kellgren-Lawrence grade III or IV osteoarthritis 3. No response to conservative treatment 4. Positive response to diagnostic geniculate nerve block

Exclusion criteria

Exclusion criteria: 1. Acute knee pain with inflammation 2. Taking anticoagulant 3. History of knee surgery 4. Serious psychiatric/neurological problems 5. Known radiculopathy 6. Intraarticular injection during previous 3 months : steroids, hyaluronic acid 7. Previous RF treatment 8. Connective tissue disease affecting knee

Design outcomes

Primary

MeasureTime frame
Pain Score Preintervention, Postintervention 1st, 2nd, 4th, 6th, 8th, 10th, 12th month Numerical Rating Scale (NRS)

Secondary

MeasureTime frame
Knee function and Patient Satisfaction Preintervention, Postintervention 1st, 2nd, 4th, 6th, 8th, 10th, 12th month Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and patient global impression,Procedural Complication Preintervention, Postintervention 1st, 2nd, 4th, 6th, 8th, 10th, 12th month Descriptive Data

Countries

Thailand

Contacts

Public ContactWanwipha Malaithong

Ramathibodi Hospital

mwanwipha@gmail.com0818891390

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026