Safety study of Vernonia cinerea lozenge in Thai healthy volunteers

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

TCTR

Registry ID

TCTR20170105002

Enrollment

Registered

2017-01-05

Start date

2017-02-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy volunteers &#45

Interventions

Herbal medicine&#44

the Vernonia cinerea extraction and prepare to lozenge dosage form. &#45

Administer 1 tablet 3 times a day aftermeal for 4 weeks. &#45

Administer 1 tablet every 2 hours for the total of 6 tablets a day for 4 weeks.

Experimental Other

VC lozenges

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: - BMI 18-25 kg/m2 - Healthy as evaluated from physical examination, EKG, blood exam, vital signs - Not pregnant - Willing to attend the study

Exclusion criteria

Exclusion criteria: - Have the illness that may be in danger for the subjects e.g., G6PD deficiency, Methemoglobinemia, other chronic diseases that physician consider to be not suitable for the study. - Current smoking - Current alcohol addication - Current drug of abuse - Having used other lozenges continuously, and cannot stop using - Lactating women - Having attended other study

Design outcomes

Primary

Measure	Time frame
Safety data 4 Laboratory, physical examinations and clinical observation	—

Secondary

Measure	Time frame
Side effects of acetaminophen/tramadol rectal suppository in 24 hours Questionaire	—

Countries

Thailand

Contacts

Public ContactSiripan Phattanarudee

Chulalongkorn University

siripan.p@pharm.chula.ac.th081-342-8785

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026