Plasma colistin trough level as a predictor for early colistin nephrotoxicity in patients receiving intravenous colistin methanesulfonate

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

TCTR

Registry ID

TCTR20161227001

Enrollment

Registered

2016-12-27

Start date

2016-05-06

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute kidney injury Nephrotoxicity

Interventions

Screening

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. â‰¥ 18-years old Thai, in-patients receiving colistin methanesulfonate 2. Hemodynamic stability

Exclusion criteria

Exclusion criteria: 1. Preexisting stage G4 or G5 chronic kidney disease 2. Receiving acute hemodialysis within 24 hr after an initiation of colistin methanesulfonate 3. Pregnancy

Design outcomes

Primary

Measure	Time frame
plasma colistin day 4 after the initiation of colistin methanesulfonate high-performance liquid chromatography	—

Secondary

Measure	Time frame
plasma neutrophil gelatinase-associated lipocalin day 4 after the initiation of colistin methanesulfonate enzyme-linked immunosorbent assay	—

Countries

Thailand

Contacts

Public ContactManeerut Limjariyakul

Chulalongkorn University

lim_mnr@hotmail.com+668-3773-5388

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026