Effect of Various Cryotherapy Applications on Postoperative Pain in Molar Teeth with Symptomatic Apical Periodontitis: Prospective Clinical Trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

TCTR

Registry ID

TCTR20161221004

Enrollment

100

Registered

2016-12-21

Start date

2015-12-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health patients with tooth requiring root canal treatment Endodontics temperature reduction cryotherapy postoperative pain

Interventions

without cryotherapy application,intracanal cryotherapy application,intraoral cryotherapy application,extraoral cryotherapy application

Active Comparator Procedure/Surgery,Experimental Procedure/Surgery,Experimental Procedure/Surgery,Experimental Procedure/Surgery

control,intracanal cryotherapy application,intraoral cryotherapy application,extraoral cryotherapy application

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients older than 18 years old Patients without any systematic diseases Tooth with symptomatic apical periodontitis Vital molar tooth

Exclusion criteria

Exclusion criteria: Patients taken drugs within 24 hours Retreatment cases Tooth with periapical lesion

Design outcomes

Primary

Measure	Time frame
Pain-VAS scale 1 week Vas scale	—

Secondary

Measure	Time frame
palpation, percussion 1 week VAS scale	—

Countries

Turkey

Contacts

Public ContactHakan Arslan

Ataturk University

dt_hakan82@hotmail.com05339351238

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026