Thoracic endovascular aortic repair (TEVAR) in the treatment of acute uncomplicated descending aortic dissection. acute uncomplicated descending aortic dissection Thoracic endovascular aortic repair
Conditions
Interventions
All patients were treated with antihypertensive medications (calcium-
channel blockers,
nitroglycerin,
beta blockers,
or a combination). The initial goals for medical therapy were to reduce SBP to 100 to 120 mmHg,
heart rate to 60 to 70 beat per minute,
and to relieve pain. If chest pain was persistent,
a narcotic analgesic (morphine hydrochloride) was administered intravenously in all patients. ,The TEVAR will be performed within 8 to 14 days of the onset of dissection. The proximal landing zone had
medical treatment alone,TEVAR plus medical treatment
Sponsors
Faculty of Medicine, Siriraj Hospital
Cardio-
Thoracic Surgery division
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: The patients who presenting with an acute uncomplicated descending aortic dissection.
Exclusion criteria
Exclusion criteria: Signs and symptoms of acute complications Malperfusion, rupture, intractable pain, uncontrolled hypertension Aortic diameter > 5.5 cm Anatomical not suitable for TEVAR aortic kinking > 75°, aortic diameter ( 42 mm.) Traumatic aortic dissection Connective tissue disease (ie. Marfan syndrome)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The freedom from all adverse events at 1 year 1 year after end of the intervention Standard follow-up clinical evaluations and CT angiography were performed at 1, 3, 6 and 12 months | — |
Secondary
| Measure | Time frame |
|---|---|
| all-cause death at 30 days and 1 year, aorta-related death and aortic remodeling 1 year after end of the intervention clinical evaluations and follow CT angiography | — |
Countries
Thailand
Contacts
Public ContactWorawong Slisatkorn
Division of Cardio-Thoracic Surgery, Department of Surgery, Siriraj Hospital, Mahidol University
Outcome results
None listed