superficial second degree burn wound ≤ 15 % Total body surface area(TBSA) at trunk and extremities Age 18-
Conditions
Interventions
1% Silver Sulfadiazine,1% Silver Sulfadiazine with Zinc containing formula
Placebo Comparator Drug,Active Comparator Drug
Control group,Studied group
Sponsors
Faculty of medicine, Siriraj Hospital, Mahidol University, Thailand
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: superficial second degree burn wound ≤ 15 % Total body surface area(TBSA) at trunk and extremities Age 18-60 years Came to get treatment in 24 hrs post injury
Exclusion criteria
Exclusion criteria: Patient with underlying with immunocompromised disease such as DM, SLE, Liver and Renal disease Patient with History of taking immunosuppressive medication Patient with History of allergy to silver, zinc metal or sulfonamide medication Patient that came to get treatment after 24 hrs post injury Pregnancy patient
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complete healing day of burn wound day of wound complete healing days | — |
Secondary
| Measure | Time frame |
|---|---|
| Effect of cream on wound pain evaluate every 3 days after dressing change 30 mins 0-10 numeric score,Blood level of Zinc in studied group Take blood exam at day0, day6 and day12 post injury mg/dL ,Burn wound infection day 6 and 12 post injury wound swab culture > 10(5) CFU/HPF | — |
Contacts
Public ContactKusuma Chinaroonchai
Division of Trauma Surgery, Department of Surgery, Faculty of Medicine, Siriraj Hospital,
Outcome results
None listed