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Sprayed 0.3% Benzydamine Hydrochloride on laryngeal mask airway increases the number of patients without postoperative sore throat.

Sprayed 0.3% Benzydamine Hydrochloride on laryngeal mask airway increases the number of patients without postoperative sore throat after general anesthesia.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20161127002
Enrollment
Unknown
Registered
2016-11-27
Start date
2014-05-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sore throat Postoperative sore throat Benzydramine hydrochlorides

Interventions

4 puffs of Normal Saline sprayed at laryngeal mask airway cuff before insertion,4 puffs of Benzydramine hydrochlorides sprayed at laryngeal mask airway cuff before insertion
Placebo Comparator No treatment,Experimental Drug
Normal Saline,Benzydramine hydrochlorides

Sponsors

Mahidol University
Lead Sponsor
Faculty of Medicine Siriraj Hospital
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: ASA physical status 1-3, scheduled for general anesthesia

Exclusion criteria

Exclusion criteria: Allergy to study drugs, gastrointestinal bleeding, severe liver and kidney disease, pregnant or lactating woman, full stomach patient, obesity (BMI > 30 kg/sq. m.)the operation of oral cavity and neck, upper respiratory tract infection, upper airway abnormality, pre-existing sore throat, retained naso/orogastric tube, duration of anesthesia less than 30 minutes.

Design outcomes

Primary

MeasureTime frame
Number of postoperative sorethroat patients First and Forth hour postoperatively Verbal numerating scale—

Secondary

MeasureTime frame
dysphagia, dysphonia, First and Forth hour postoperatively Verbal rating scale—

Countries

Thailand

Contacts

Public ContactSathit Chairatthanawanit

Lecturer

Sathit13@hotmail.com0817902397

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026