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Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.critically – ill trauma patient (Definition was patient that has one clinical of one system of organ failure) 2.Age 18-65 year 3.Trauma patient that was got treatment in Siriraj Hospital in 6 hrs of post injury period. 4.No history of using immunosuppressive agents such as steriods or NSAID medication prior to injury period. 5.No underlying diseases that can interfere serum albumin level sush as liver disease, kidney disease, or autoimmune disease.
Exclusion criteria
Exclusion criteria: 1.non critically-ill trauma patient 2.Age 65 year 3.Trauma patient that was got treatment in Siriraj Hospital after 6 hrs of post injury period. 4.History of using immunosuppressive agents such as steriods or NSAID medication prior to injury period. 5.Patient with underlying diseases that can interfere serum albumin level sush as liver disease, kidney disease, or autoimmune disease. 6.Cannot get informed consent 7.Patient that got albumin supplement therapy as treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Correlation between changing of serum albumin level and cytokine level in critically ill trauma pati 6,24,48,120 (hrs) Blood level of albumin and cytokines | — |
Secondary
| Measure | Time frame |
|---|---|
| mortality rate admit - day 28 death rate ,Length of hospital stay admit - discharge time from admit to discharge,infection rate admit-day 28 event number,MODS admit-day 28 Marshall score ,Ventilator day admit-day 28 day of ventilator used,ICU stay admit-day 28 day of ICU used | — |
Countries
Thailand
Contacts
Division of Trauma Surgery, Department of Surgery,Faculty of Medicine. Siriraj Hospital, Mahidol Uni