The effects of sugar intake, versus, chewing, and control, on experimentally induced pain-pressure threshold; a randomised repeated measure study in normal participants. (the LET'SEAT study)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

TCTR

Registry ID

TCTR20161107002

Enrollment

Registered

2016-11-07

Start date

2016-11-07

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Persistent pain Obesity Overweight Health individuals Experimental Pain threshold eating chewing

Interventions

The participant will undergo six minutes of sitting inactively. EIPPT will be measured at baseline&#44

three minutes and then again five minutes after the control condition stops.,The participant will undergo six minutes of eating sweets (Bassetsâ„¢ Jelly Babies). Participants will be allowed to consu

the only stipulation being that they must have at least one in their mouth at all times and be actively eating it throughout the relevant 6 minutes. EIPPT will be measured at baseline&#44

three minutes and then again five minutes after the intervention stops.,The participant will undergo six minutes of chewing gum. EIPPT will be measured at baseline&#44

three minutes and then again five minutes after the intervention stops.

No Intervention No treatment,Active Comparator Behavioral,Experimental Behavioral

Control,Eating sweets,Chewing gum

Eligibility

Sex/Gender

All

Age

16 Years to 50 Years

Inclusion criteria

Inclusion criteria: Healthy (self-reported) University students and aged between 16-50 years of age.

Exclusion criteria

Exclusion criteria: People with any metabolic or other condition who have been advised to avoid eating sweets or other high calorie, low nutrition foods, any condition which could alter pain sensitivity such as neuropathic disorders, persistent pain, any present (or history, over the preceding six months) of medical problems of the upper limb, taking any analgesic medication (prescription or non-prescription), allergy to the sweets/chewing gum which will be used in the study, inability to, or any doubt of ability to, give Informed Consent.

Design outcomes

Primary

Measure	Time frame
experimentally induced pain-pressure threshold (EIPPT). Pre and post intervention Wagner Force Oneâ„¢ FDIX digital pressure algometer	—

Secondary

Measure	Time frame
not applicable not applicable not applicable	—

Countries

Contacts

Public ContactCormac Ryan

Teesside University

c.ryan@tees.ac.uk00441642

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026

The effects of sugar intake&#44; versus&#44; chewing&#44; and control&#44; on experimentally induced pain&#45;pressure threshold; a randomised repeated measure study in normal participants. (the LET&#39;SEAT study)