Serum Angiotensin II Level in Chronic Hepatitis C Patients Who Achieved Sustained Virologic Response after Direct Antiviral Agent Therapy

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

TCTR

Registry ID

TCTR20161025001

Enrollment

Registered

2016-10-25

Start date

2016-10-31

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic hepatitis C Patients who Achieved Sustained Virologic Response after Direct Antiviral Agent Therapy Angiotensin II Hepatitis C Direct antiviral agent Fibrogenesis

Interventions

Chronic hepatitis C patients treated with direct antiviral therapy

Basic Science

HCVDAA

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age >/= 18 years old Chronic hepatitis C infection Direct antiviral agent therapy

Exclusion criteria

Exclusion criteria: Hepatitis B coinfection HIV coinfection Other known etiology of liver disease e.g. alcoholism, autoimmune hepatitis, biliary cirrhosis, congestive hepatopathy, congenital or hereditary liver disease, infiltrative liver disease Decompensated cirrhosis Hepatocellular carcinoma Immunosuppressive agent used Renin inhibitor, angiotensin converting enzyme inhibitor, angiotensin receptor blocker, or aldosterone antagonist used Diuretic agent used Oral contraceptive therapy Renin secreting tumor Renal hypertension or malignant hypertension (BP > 220/120 mmHg) Chronic kidney disease, eGFR < 60 ml/min/m2 Incomplete treatment Who dose not achieve sustained virologic response

Design outcomes

Primary

Measure	Time frame
Serum Angiotensin II Level Start treatment and sustained virologic response ELISA	—

Secondary

Measure	Time frame
Serum TGF-beta 1, TIMP-1, and MMP 9 Levels Start treatment and sustained virologic response ELISA	—

Countries

Thailand

Contacts

Public ContactNicha Teeratorn

Division of Gastroenterology, King Chulalongkorn Memorial Hospital

nicha.teeratorn@gmail.com0898588947

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026