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The Efficacy of Aloe Vera Gel in Postprocedural Wound Care after Fractional 1550 nm Erbium-Doped Fiber Laser

The Efficacy of Aloe Vera Gel in Postprocedural Wound Care after Fractional 1550 nm Erbium-Doped Fiber Laser

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20161010006
Enrollment
Unknown
Registered
2016-10-10
Start date
2014-09-29
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Participants with mild to moderate severity for skin photoaging&#44

Interventions

A compound of aloe vera gel contains 87.40% of inner leaf gel&#44
edetate disodium&#44
bronopol&#44
sodium metabisulfite&#44
methylparaben&#44
propylparaben&#44
butylene glycol&#44
carbomers&#44
triethanolamine andpurified water(Burnova Gel manufactured by BERICH (Thailand) Co.&#44
Ltd.). Thai FDA number is G 634/53,Placebo Gel manufactured by BERICH (Thailand) Co.&#44
Ltd.
Experimental Drug,Placebo Comparator Drug
Aloe vera gel,placebo

Sponsors

Skin Center, Faculty of Medicine, Srinakharinwirot University
Lead Sponsor
BERICH (Thailand) Co.&#44
Collaborator
Ltd.
Collaborator

Eligibility

Sex/Gender
All
Age
28 Years to 80 Years

Inclusion criteria

Inclusion criteria: Participants with mild to moderate severity for skin photoaging,classified by Glogau’s classification were enrolled. Photoaging with Glogau’s classification define as mild severity with as a mild pigmentory changes, no keratosis and minimal wrinkle and moderate severity as an early visible brown spots, palpable keratosis but not visible and parallel smile lines.

Exclusion criteria

Exclusion criteria: Concurrent skin conditions or any underlying diseases that may affect wound healing process were excluded.

Design outcomes

Primary

MeasureTime frame
Clinical erythema score 5 visits : at the baseline, immediately after laser, at day 3, day 7 and day 14 physician assessed—

Secondary

MeasureTime frame
erythema index and melanin index 5 visits : at the baseline, immediately after laser, at day 3, day 7 and day 14 Mexameter,transepidermal water loss (TEWL) 5 visits : at the baseline, immediately after laser, at day 3, day 7 and day 14 Tewameter,Skin capacitance 5 visits : at the baseline, immediately after laser, at day 3, day 7 and day 14 Corneometer,The daily self-assessment report for wound recovery daily assessed by participants,global satisfaction score 4 visits : immediately after laser, at day 3, day 7 and day 14 assessed by participants—

Contacts

Public ContactMontree Udompataikul

Skin Center, Faculty of Medicine, Srinakharinwirot University

umontree@gmail.com02-259-4260

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026