LDL cholesterol LDL cholesterol,
Conditions
Interventions
180 ml of soy milk which contains 4.5 gm of fat,
5 gm of protein,
and 12 gm of carbohydrate fortified with 1 gm phytosterol and 5 gm inulin,180 ml of soy milk which contains 4.5 gm of fat,
and 12 gm of carbohydrate without phytosterol or inulin
Experimental Dietary Supplement,Placebo Comparator Dietary Supplement
soy milk fortified with phytosterol and inulin,unfortified soy milk
Sponsors
none
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) more than 18 years of age 2) had LDL-c of 130-190 mg/dL without lipid lowering medication 3) consent to join the study
Exclusion criteria
Exclusion criteria: 1) LDL-c of >190 mg/dL 2) high risk for cardiovascular disease as determined by Framingham risk assessment of >20% in 10 years 3) LDL-c of >160 mg/dL with risk of >10% in 10 years without receiving lipid lowering medication 4) coronary heart disease, symptomatic carotid artery disease, abdominal aortic aneurysm, or peripheral arterial disease 5) type 1 or type 2 diabetes with hemoglobin A1c (HbA1c) of >7.5% 6) secondary dyslipidemia from nephrotic syndrome, hypothyroidism, hepatic disorder, Cushing’s syndrome, or other conditions 7) malabsorption 8) allergy to soy or soy product
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| LDL cholesterol 2, 4, 8, 12 weeks lipid profile | — |
Secondary
| Measure | Time frame |
|---|---|
| total cholesterol, HDL cholesterol, triglyceride 2, 4, 8, 12 weeks lipid profile | — |
Countries
Thailand
Contacts
Public ContactMayuree Homsanit
Mahidol University
Outcome results
None listed