Osteoarthritis of the knee Sahastara remedy Pharmacokinetics Herbal medicine Piperine
Conditions
Interventions
Sponsors
National Research Council of Thailand (NRTC)
Faculty of Medicine,
Thammasat University
Eligibility
Sex/Gender
All
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Both sex age between 20-45 years 2. No pregnancy 3. No Serious Medical Condition evaluated by Physical Examination and Laboratory results in 1 month before study 4. No Supplementary and/or Vitamin during the study 5. Able to follow suggestion during the study
Exclusion criteria
Exclusion criteria: 1. Have uncontrolled Hypertension (BP>140/90) 2. BMI > 30 3. Have Serious Medical condition such as Serious Peptic Ulcer, Congestive hearth disease, liver and renal dysfunction 4. On during use medicine including rifampicin, phynytoin, Propranolol, Theophylline 5. Hypersensitivity on herbal medicine
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pharmacokinetics parameters of Piperine 0,0.5,1,2,3,4,6,9,12,18,24,48 hour Piperine content is determined by LC-MS/MS. Then,the pharmacokinetics parameters was calculated by c | — |
Secondary
| Measure | Time frame |
|---|---|
| no no no | — |
Countries
Thailand
Contacts
Public ContactPuritat Kanokkangsadal
Faculty of Medicine, Thammasat University
Outcome results
None listed