What is sensitivity and specificity of spraying of methylene blue intra-
Conditions
Interventions
Used 0.1% methylene blue 1 ml spray during intra-
operative thyroidectomy.Parathyroid gland will metabolized methylene blue and regain to its own color within less than 5 minute (faster than other perithyroidal softissue).
Experimental Procedure/Surgery
spraying of methylene blue intra-
operative thyroidectomy field
Sponsors
Faculty of Medicine Khon Kaen university
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1.Patient who on going to thyroid lobectomy 2.Age >= 18 years old
Exclusion criteria
Exclusion criteria: 1.Patient who used to undergo thyroid surgery 2.Patient who allergy to methylene blue 3.Pregnancy 4.Patient who on going to endoscopic thyroid surgery 5.Patient who on MAOIs such as tranylcypromine, isocarboxazid , phenelzine or on medical that has similar pharmacological effect such as furazolidone, isoniazid, procarbazine, linezolid 6.G6PD deficiency
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sensitivity of Intra-operative methylene blue spray intra-operative pathohistology,specificity of Intra-operative methylene blue spray intra-operative pathohistology | — |
Secondary
| Measure | Time frame |
|---|---|
| PPV of Intra-operative methylene blue spray intra-operative pathohistology,NPV of Intra-operative methylene blue spray intra-operative pathohistology | — |
Countries
Thailand
Contacts
Public ContactThipphailin Jungtrakul
Khon Kaen University
Outcome results
None listed