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A comparison of Phenylephrine Administration between Intravenous Bolus and Slow Injection in Treatment of Spinal Anesthesia-induced Hypotension on Bradycardia and Other Side Effects in Patients Undergoing Cesarean Section

A comparison of Phenylephrine Administration between Intravenous Bolus and Slow Injection in Treatment of Spinal Anesthesia-induced Hypotension on Bradycardia and Other Side Effects in Patients Undergoing Cesarean Section

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20160426003
Enrollment
58
Registered
2016-04-26
Start date
2016-04-30
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy prenancy phenylephrine hypotension spinal anesthesia cesarean section bolus slow

Interventions

Bolus injection of phenylephrine 100 mcg intravenous,Continuous slow injection within 30 seconds of phenylephrine 100 mcg intravenous
Experimental Drug,Experimental Drug
Bolus injection,Slow injection

Sponsors

none
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.ASA physical status I or II 2.Age ≥ 18 years old 3.Singleton baby 4.Term pregnancy (GA ≥ 37 weeks)

Exclusion criteria

Exclusion criteria: 1. Pregestational or gestational hypertension 2. Cardiovascular disease 3. Cerebrovascular disease 4. Obstetric complications (eg. abruptio placenta , placenta previa) 5. Known abnormal fetus 6. History use of monoamine oxidase inhibitor (MAOI) or other drugs that prlong heart conduction 7. Other medications except spinal bupivacaine and spinalmorphine before baby delivery

Design outcomes

Primary

MeasureTime frame
Incidence of bradycardia Immediately after phenylephrine administration and before baby delivery Number and percentage—

Secondary

MeasureTime frame
Incidence of the other side effects Immediately after phenylephrine administration and before baby delivery Number and percentage—

Countries

Thailand

Contacts

Public ContactRatikorn Anusorntanawat

Chaophrayayommarat hospital

netanesth@hotmail.com+66819424915

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026