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Histological Evaluation and Inflammatory Response of Different Abutment Materials: An Experimental Study in Human

Histological Evaluation and Inflammatory Response of Different Abutment Materials: An Experimental Study in Human

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20160411003
Enrollment
Unknown
Registered
2016-04-11
Start date
2015-05-25
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

edentulous space at posterior area no grafting needed enough width of attach gingiva

Interventions

Randomly assigned 3 different abutment materials
titanium&#44
zirconia&#44
gold alloy&#44
to the patients on the surgery day. 8 week after&#44
cut the soft tissue 1mm around the abutments and remove the tissue together with the abutment to process for histological examination.,Randomly assigned 3 different abutment materials
cut the soft tissue 1mm around the abutments and remove the tissue together with the abutment to process for histological examination.
type of abutment material
titanium,type of abutment material
zirconia,type of abutment material

Sponsors

90th Anniversary of Chulalongkorn University Fund (Ratchadaphiseksomphot Endowment Fund)
Lead Sponsor
90th Anniversary of Chulalongkorn University Fund (Ratchadaphiseksomphot Endowment Fund)
Collaborator

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: Edentulous space at posterior maxilla or mandible area Tooth extraction at least 4 months prior to implant placement Adequate bone quantity at the experimental site to allow the insertion of 5.0mm diameter implants Sufficient band of keratinized mucosa (>5 mm) Inter-arch space (> 5mm) Fixture level at least 3mm deeper from soft tissue margin Non-smoker No conditions requiring chronic routine prophylactic use of antibiotics (e.g. history of rheumatic heart disease, bacterial endocarditis, cardiac valvular anomalies, prosthetic joint replacements) No systemic diseases which could influence the outcome of the therapy (e.g. diabetes, osteoporosis, bisphosphonate medication) Not being a pregnant woman Not being a handicap that would interfere with the ability to perform adequate oral hygiene and attending all follow-up procedures

Exclusion criteria

Exclusion criteria: smoker being pregnant

Design outcomes

Primary

MeasureTime frame
attachment evaluation 8 weeks after implant surgery percentage of attachment seen in histological slide

Secondary

MeasureTime frame
inflammatory response 8 weeks after implant surgery inflammatory grade scale

Countries

Thailand

Contacts

Public ContactChalearmpol Leeviroj

Esthetic Restorative and Implant Dentistry Chulalongkorn University

esthetic.implant.chula@gmail.com+66822188662

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026