chronic obstructive pulmonary disease
Conditions
Interventions
COPD patients who met the inclusion criteria will be performed diaphragm ultrasound to measure thickening fraction of the diaphragm and diaphragm excursion during tidal breathing,
sniff test,
and maximum effort. ,Subjects in control arm who met the inclusion criteria will be performed diaphragm ultrasound to measure thickening fraction of the diaphragm and diaphragm excursion during tidal
and maximum effort.
Diagnostic,Diagnostic
COPD patients,Control arm
Sponsors
Faculty of Medicine Siriraj Hospital, Mahidol Univesity
Eligibility
Sex/Gender
All
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: Study population (n = 80) - Age > 40 years - COPD as defined by GOLD criteria (post-bronchodilator FEV1/FVC 40 years - Normal pulmonary function determined by standard spirometry
Exclusion criteria
Exclusion criteria: Study population - History of acute exacerbations of COPD within the past 3 months - History of thoracic surgery - Known diaphragmatic paralysis or chronic neuromuscular disease Control population - History of thoracic surgery - Known diaphragmatic paralysis or chronic neuromuscular disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Correlation between diaphragm contractile activity and the degree of airflow obstruction N/A Diaphragm ultrasound,Diaphragm contractile activity between COPD patients and control population N/A Diaphragm ultrasound | — |
Secondary
| Measure | Time frame |
|---|---|
| Factor associated with diaphragm dysfunction - N/A | — |
Countries
Thailand
Contacts
Public ContactNuttapol Rittayamai
Faculty of Medicine Siriraj Hospital
Outcome results
None listed