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Randomized,double-blind,placebo-controlled study of ingestion of yogurt containing Lactobacillus acidophilus to improve vaginal pH in postmenopausal women

Randomized, Double-blind, Placebo-Controlled Study of Ingestion of Yogurt Containing Lactobacillus acidophilus to Improve Vaginal pH in Postmenopausal Women

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20160311002
Enrollment
14
Registered
2016-03-11
Start date
2012-06-01
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

vaginal pH in menopause yogurt&#44

Interventions

Test product In joint research with Institute of Food Research and Product Development&#44
Kasetsart Universiry. We produced two types of yogurt to use in this study: (1) single culture yoghurt (L. acidophilus TISTR 450)&#44
(2) mixed culture yoghurt (L. delbrueckii subsp. bulgaricus TISTR 892 and S. thermophilus TISTR 894). Texture of 2 types of yoghurt were not different with smooth surface and texture white opaque colo
respectively ,Test product In joint research with Institute of Food Research and Product Development&#44
control yogurt (L. delbrueckii subsp. bulgaricus &#44
S. thermophilus),Yogurt Containing Lactobacillus acidophilus

Sponsors

-
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria consisted of: (i) post menopause woman , (ii) the ability to follow up, (iii) the will to cooperate during the study

Exclusion criteria

Exclusion criteria: exclusion criteria were: (i) hypersensitivity to any ingredient in the study product, (ii) the use of systemic or local hormonal therapy, (iii) the use of drug that influences pH in vagina, (iv) sexual intercourse two days before study, (v) immunocompromise host, (vi) active infection in genital and /or pelvic organs

Design outcomes

Primary

MeasureTime frame
Vaginal pH 2 week Litmus paper

Secondary

MeasureTime frame
Presence of the applied Lactobacillus acidophilus in the studied women 2 week bacterial culture

Countries

Thailand

Contacts

Public ContactJittima Manonai

Division of Obstetrics and gynecology, Falculty of Medicine Ramathibodi Hospital

jittima_pom@yahoo.com0816207407

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026