Efficacy and Safety in Self-Prepared Nasal Saline Irrigation and Clinical Outcome in Patient with Allergic Rhinitis

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20160120001

Enrollment

264

Registered

2016-01-20

Start date

2016-01-20

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

1.Allergic rhinitis 1.Allergic rhinitis 2.Self prepared 3.Saline irrigation 4.Hypertonic saline 5.Isotonic saline

Interventions

Adjuvant therapy 0.9% NaCl irrigate 2 time per day&#44

80 ml per nostril ,Adjuvant therapy 1.8% NaCl irrigate 2 time per day&#44

80 ml per nostril ,Adjuvant therapy 0.9% NaCl irrigate 2 time per day&#44

80 ml per nostril

Experimental Other,Experimental Other,Active Comparator Other

normal saline ,Hypertonic saline ,Normal saline (klean & kare)

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Age 18-65 years,all gender. 2.Underlying disease is Allergic disease. 3.Have a running nose with these symtoms at least 1 symptom 3.1 sneezing 3.2 congestion 3.3 itching 3.4 conjunctivitis

Exclusion criteria

Exclusion criteria: 1.Seafood allergy. 2.Have an abnormal in internal nostril. 3.Have a sign of infection (fever,body temperature>38 celcius or purulent in nostril or pain in nostril or get an antibiotic) 4.Tumor in nostril. 5.Abnormal structure of septum nose. 6.Abnormal mucocialiary

Design outcomes

Primary

Measure	Time frame
Quality of life At 1 months after end of intervention Rcq-36	—

Secondary

Measure	Time frame
Total nasal symptom score At 1 months after end of intervention TNSS	—

Countries

Thailand

Contacts

Public ContactKrongkwan Duangpawang

Faculty of pharmacy

Krongkwan.d@msu.ac.th+66 43-754-360

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026

Efficacy and Safety in Self&#45;Prepared Nasal Saline Irrigation and Clinical Outcome in Patient with Allergic Rhinitis