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Effect of xanthones extract from mangosteen on reduced insulin resistance, visceral fat, and fatty liver due to reduction of inflammatory markers and oxidative stress in pre-diabetes/diabetes patients

Effect of xanthones extract from mangosteen on reduced insulin resistance, visceral fat and fatty liver due to reduction of inflammatory markers and oxidative stress in pre-diabetes/diabetes patients.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20151215003
Enrollment
240
Registered
2015-12-15
Start date
2016-01-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Xanthones extract&#44

Interventions

Starch component,Xanthones component
Placebo Comparator Drug,Active Comparator Drug
Control,Active (Xanthones)

Sponsors

National Research Council of Thailand (NRCT)
Lead Sponsor
National Research Council of Thailand (NRCT)
Collaborator

Eligibility

Sex/Gender
All
Age
25 Years to 65 Years

Inclusion criteria

Inclusion criteria: prediabetes patients, type 2 diabetes patients

Exclusion criteria

Exclusion criteria: type 1 diabetes renal failure with serum creatinine 2 0 md dL secondary cause of chronic hepatitis Liver failure with AST and ALT over than 2.5 times of upper limit heavy alcoholic drinking receiving anti hyperglycemic drugs TZD DDP IV inhibitor insulin GLP 1 agonist and antihyperlipid drugs fenofibrate gemfibrozile and ezetrol receiving other herbal secondary cause of hyperglycemia history of inflammatory and infection diseases pregnancy women history of gall stone or cholecystectomy

Design outcomes

Primary

MeasureTime frame
metabolic profiles, FBG, HbA1c, lipid profiles, insulin resistance, visceral fat and fatty liver 1 year t-test—

Secondary

MeasureTime frame
inflammatory markers and oxidative stress markers 1 year t-test—

Countries

Thailand

Contacts

Public ContactSomlak Chuengsamarn

Srinakarindwirot University

somlukc@swu.ac.th037-395085

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026