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Effect of yogurt contained probiotic Lactobacillus fermentum SD11 on prevention of oral disease in human volunteers

Effect of yogurt contained probiotic Lactobacillus fermentum SD11 on prevention of oral disease in human volunteers

Status
Active, not recruiting
Phases
Phase 1Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20151214003
Enrollment
40
Registered
2015-12-14
Start date
2016-01-05
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Subjects had to have good general health condition

Interventions

yogurt contained Lactobacillus fermentum SD11 ,yogurt contained L. bulgaricus
Group A received yogurt contained L. fermentum SD11 once daily for 1 month. ,subjects were randomly assigned to group A or B&#44
Group B received yogurt contained L. bulgaricus once daily for 1 month
Active Comparator Dietary Supplement,Placebo Comparator Dietary Supplement

Sponsors

The Office of the Higher Education Commission
Lead Sponsor
National Research Council of Thailand (NRTC)
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to 25 Years

Inclusion criteria

Inclusion criteria: Subjects had to have good general health condition

Exclusion criteria

Exclusion criteria: i habitual consumption of probiotics ii systemic antibiotic medication taken within 2 weeks iii allergy to cows milk lactose intolerance severe food allergy and iv systemic diseases relate with immunity problem V dental caries more than 2 teeth VI smoking

Design outcomes

Primary

MeasureTime frame
decrease oral pathogen end of the intervention, 1, 2, 3, 4 weeks after end of the intervention mutans streptococci (MS) count, lactobacilli count and yeasts count, anaerobe bacteria count

Secondary

MeasureTime frame
preventing and treating gingivitis end of the intervention, 4 weeks after end of the intervention plaque index (PI), gingival index (GI),persistence of Lactobacillus fermentum SD11 1, 2, 3, 4 weeks after end of the intervention assessment of persistence of Lactobacillus fermentum SD11,product side effect each time that recive product assessment of product side effect ,product satisfaction end of the intervention assessment of product satisfaction

Countries

Thailand

Contacts

Public ContactPraphansri Ruangsri

Prince of Songkla University

praphansri@yahoo.com66+74+429877

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026