effectiveness of 14-
Conditions
Interventions
Amoxicillin 500 mg QID,
rabeprazole 20 mg BID,
clarithromycin MR 1000 mg OD,
14 days,-
First 5 days : Amoxicillin 1,
00 mg BID,
rabeprazole 20 mg BID
-
Next 5 days: Rabeprazole 20 mg BID,
metronidazole 400 mg TID
Active Comparator Drug,Active Comparator Drug
day standard triple therapy with four timesâ€daily dosing of amoxicillin,sequential therapy
Sponsors
The human ethics committee of thammasat university
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: who underwent gastroscopic examination at Thammasat University Hospital, for dyspeptic symptoms between Februry 2015 and Februry 2016 were enrolled. After the endoscopy, those with diagnosis of non-ulcer dyspepsia, which was established during gastroscopy with normal finding or mild gastritis, were considered for entry in this study.
Exclusion criteria
Exclusion criteria: - patients with a history of prior H. pylori eradication - previous gastric surgery - pregnancy, lactation, major systemic diseases, cardiovascular disease - administration of antibiotics and PPI drugs in the preceding 4 weeks - allergy to any one of the given medication in the regimens
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effectiveness 4 weeks after intervention Helicobacter Pylori eradication | — |
Secondary
| Measure | Time frame |
|---|---|
| Compare effectiveness of Helicobacter Pylori eradication 4 weeks after intervention 14-day standard triple therapy with four timesâ€daily dosing of amoxicillin and sequential therapy | — |
Countries
Thailand
Contacts
Public ContactDr.Kittichet Phiphatpatthamaamphan
ktcppa@gmail.com
Outcome results
None listed