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Investigation of Effects of Midazolam on Pulsatile Ocular Blood Flow and Intraocular Pressure in Patients who have Spinal Block

Investigation of Effects of Midazolam on Pulsatile Ocular Blood Flow and Intraocular Pressure in Patients who have Spinal Block

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20151207001
Enrollment
Unknown
Registered
2015-12-07
Start date
2010-01-01
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Other intraoperative complications of eye and adnexa&#44

Interventions

0.1&#45
0.2 mg/kg/h infusion during the surgery
midazolam

Sponsors

Eskisehir Osmangazi University
Lead Sponsor
Eskisehir Osmangazi University
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Ages between 18-75 years, who had spinal anesthesia for urologic and orthopedic surgeries on supine position. Patients were I-II class according to American Society of Anesthesiologists (ASA)

Exclusion criteria

Exclusion criteria: Patients who had drug sensitivity, contraindication for block, difficulty of communication, uncontrolled another disease (such as diabetes mellitus, hypertension, arrhythmia, hearth disease), failure of either liver or kidney, intraocular surgery, glaucoma or corneal problem, and refraction problems (up to +3, or -3), as well as patients who uses alpha-2 receptor agonist or antagonist were excluded from the study.

Design outcomes

Primary

MeasureTime frame
intraocular pressure (IOP) during surgery Reichert Model 30 Classic Pneumatonometer

Secondary

MeasureTime frame
Ocular pulse amplitude (OPA) during surgery Reichert Model 30 Classic Pneumatonometer

Countries

turkey

Contacts

Public Contactcenk sahan

Eskisehir Osmangazi University

farassin@gmail.com+905064410277

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026