Effect of transcranial direct current stimulation on cognitive function in mild cognitive impairment

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

TCTR

Registry ID

TCTR20151125002

Enrollment

Registered

2015-11-25

Start date

2015-10-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mild cognitive impairment Transcranial direct current stimulation&#44

Interventions

real tDCS was applied 20 mins per session&#44

3 times per week for 4 weeks (12 session). Using 2 mA intensity via saline&#45

soakd 5x5 cm electrode. Anode electrode was applied at right dorsolateral prefrontal cortex ( F4 according to 10&#45

20 EEG system) and cathode was applied at left supraorbital area.,sham tDCS was applied same as real tDCS but electrical current was deliverd just 30 sec.

Experimental Device,Sham Comparator Device

real tDCS,sham tDCS

Eligibility

Sex/Gender

All

Age

45 Years to 90 Years

Inclusion criteria

Inclusion criteria: MCI patients with 1. Age 45-90 years old 2. TMSE >23/30 and Thai version of the montreal cognitive assessment (MoCA-Thai) <25/30 3. Can participate in research over the period

Exclusion criteria

Exclusion criteria: 1.contraindication to tDCS: - implanted metal devices - history of seizure - using drugs reducing seizure threshold - disorder of scalp - history of head surgery - had been unconscious for more than 15 minutes 2. neurological abnormalities show upper motor neuron signs: spasticity, hypereflexia 3.Neuropsychiatric problems 4. The level of education is lower than the fourth grade 5.using drugs effects cognitive performance; antipsychotic drugs, anticholinergic drugs, antiepileptic drugs 6.drug or alcohol abuse or dependence 7.MCI were treated with the drug during the past three months 8.vision problem that has not been corrected or color blindness

Design outcomes

Primary

Measure	Time frame
cognitive function immediate effect, 4th wk, 8th wk Rapid visual information processing (CANTAB test)	—

Secondary

Measure	Time frame
cognitive function immediate, 4th week, 8th week Spatial working memory(SWM), Pattern recognition memory(PRM), Delayed matching to sample (DMS),side effect immediate, 4th week, 8th week questionare	—

Countries

Thailand

Contacts

Public ContactKrisna Piravej

Rehabilitation department. Faculty of Medicine. Chulalongkorn University

kppmrchula@gmail.comà¸¸(66)-2256-4433

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026