The effect of a single dose dexamethasone on postoperative pain in patients ondergoing gynecological laparotomy surgery

The effect of a single dose dexamethasone on postoperative pain in patients ondergoing gynecological laparotomy surgery :A Double Blinded Randomized Controlled Trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20151116001

Enrollment

Unknown

Registered

2015-11-16

Start date

2014-06-03

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative pain after laparotomy gynecological surgery dexamethasone postopertive pain gynecological surgery laparotomy surgery

Interventions

8mg intravenous dexamethasone immediately after intubation

Placebo Comparator Drug

dexamethasone

Eligibility

Sex/Gender

Female

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.ASA physical status I or II 2.aged between 18-65 years 3.undergoing elective gynecological laparotomy surgery under general anesthesia

Exclusion criteria

Exclusion criteria: 1.diabetic mellitus 2.treatment with steroids 3.obesity 4.use of opioid or analgesic drug within one month prior to the study 5.history of alcohol or drug abuse 6.pregnancy 7.undergoing surgical staging surgery 8.history of chronic pain 9.history of peptic ulcer or gastritis 10.patietns who refused

Design outcomes

Primary

Measure	Time frame
postoperative pain 24hours postoperative pain score	—

Secondary

Measure	Time frame
total morphine consumption 24hours postoperative milligrams	—

Countries

Thailand

Contacts

Public ContactPornpatra Areeruk

Ramathibodi hospital

pornpatra@yahoo.com0892154208

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026