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Non-Invasive Brain Stimulation and Physical Training in Stroke Patients with Motor Impairments

Acute and chronic effect of transcranial direct current stimulation and physical training on the neuromuscular and functional performance in chronic stroke patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20151112001
Enrollment
Unknown
Registered
2015-11-12
Start date
2015-11-16
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke Strokes Apoplexy CVA (Cerebrovascular Accident) CVAs (Cerebrovascular Accident) Cerebrovascular Accident Cerebrovascular Accidents Cerebrovascular Apoplexy Apoplexy&#44

Interventions

Transcranial direct current stimulation (tDCS) will be combined with physical exercise. tDCS is a non&#45
invasive technique that can be used to alter cortical activity and has been widely used in the treatment of several neurological disorders. A continuous weak electric current is applied to the brain v
favoring depolarization and increasing spontaneous neuronal firing rate&#44
whereas opposite effects are provoked by cathodal tDCS.,In this case&#44
instead of receiving real Transcranial direct current stimulation (tDCS) this group will receive a sham stimulation combined with physical execise. is a non&#45
whereas opposite effects are provoked by cathodal tDCS.
Experimental Other,Sham Comparator Other
Cerebral Stimulation plus physocal exercise,Sham plus physical exercise

Sponsors

Physical Activity and Health Promotion Laboratory of University of Rio de Janeiro State
Lead Sponsor
Physical Activity and Health Promotion Laboratory of University of Rio de Janeiro State
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: a) patients with right or left hemiparesis , with at least six months of the occurrence of the the stroke; b ) patients able to wander unsupervised for home march ; c ) patients enrolled in neuromotor rehabilitation program ; d ) patients with score above 36 on the Berg Balance Scale ; e) patients with a minimum score of 20 on Fulg -Meyer scale. These criteria will be obtained and judged by prior medical examination , medical history and functional evaluation.

Exclusion criteria

Exclusion criteria: Patients who do not meet the inclusion criteria of the study, or having any impediment that prevents the tests proposed and / or co-morbidity , does not control , will be excluded from this search

Design outcomes

Primary

MeasureTime frame
Strength (maximal and endurance) and Motor Control of upper and lower limbs After single session of tDCS (neuromodulation), and after 12, 24 and 36 sessions of tDCS Dynamometry, coefficient of variation between repetition of movements and Fugl Meyer Scale

Secondary

MeasureTime frame
Electromyography (EMG) and Electroencephalography (EEG) After single session of tDCS (neuromodulation), and after 12, 24 and 36 sessions of tDCS RMS and median frequency of EMG; and total power and cohenrence of EEG channels

Countries

Brazil

Contacts

Public ContactPaulo Farinatti

University of Rio de Janeiro State

pfarinatti@gmail.com+552123340775

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026