Impact on insulin sensitivity and insulin resistance after the conversion from tacrolimus twice daily to extended-release tacrolimus once daily in stable renal transplant recipients

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20151005001

Enrollment

Unknown

Registered

2015-10-05

Start date

2015-01-04

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

insulin sensitivity insulin resistance insulin sensitivity insulin resistance tacrolimus extended release tacrolimus once daily

Interventions

Conversion from tacrolimus twice daily to tacrolimus once daily

Experimental Drug

tacrolimus once daily

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: age more than 18 years old renal transplantation stable renal function

Exclusion criteria

Exclusion criteria: malignancy critical illness

Design outcomes

Primary

Measure	Time frame
insulin sensitivity and insulin resistance 4, 8, 16 weeks plasma insulin and plasma glucose	—

Secondary

Measure	Time frame
the patient satisfaction 16 weeks visual analog scale	—

Countries

Thailand

Contacts

Public ContactPrajej Ruangkanchanasetr

Phramongkutklao hospital

prajej@gmail.com081-311-7815

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026

Impact on insulin sensitivity and insulin resistance after the conversion from tacrolimus twice daily to extended&#45;release tacrolimus once daily in stable renal transplant recipients