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Comparative Study of Efficacy and Adverse Effects of Ginger Extract and Loratadine for Treatment of Allergic Rhinitis Patients (Clinical Trial Phase II)

Comparative Study of Efficacy and Adverse Effects of Ginger Extract and Loratadine for Treatment of Allergic Rhinitis Patients (Clinical Trial Phase II)

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20151001001
Enrollment
80
Registered
2015-10-01
Start date
2015-09-29
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rhinitis is broadly defined as inflammation of the nasal mucosa. It is a common disorder that affects up to 40% of the population.

Interventions

Ginger extract capsule at dose of 250 mg two times a day after meal daily for 42 days,Loratadine tablet at dose of 10 mg one times a day after morning meal daily for 42 days
Experimental Drug,Experimental Drug

Sponsors

Thai Traditional Medical Knowledge Fund
Lead Sponsor
Faculty of Medicine Thammasat University
Collaborator

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.Patients have moderate allergic rhinitis (itching and nasal obstruction,watery nasal discharge,sneezing and congestion )with a minimum total nasal symptom score 5 point 2.These patients do not have respiratory disease such as tuberculosis, nasal polyps. 3.These patients do not have history of disease: heart disease, kidney disease, liver disease, epilepsy, high blood pressure and severe asthma. 4.These patients are not pregnanct or breastfeeding. 5.These patients have normal BMI and vital signs.

Exclusion criteria

Exclusion criteria: 1.Those who have taken anti-coagulant and anti-platelet aggregation medications. 2.Those who get serious side effects from Loratadine and ginger allergy. 3.Communication problems especially listening and interview.

Design outcomes

Primary

MeasureTime frame
nasal symptom 42 days total nasal symptom score ,nasal patency 42 days Acoustic rhinometry

Secondary

MeasureTime frame
Quality of Life 3 weeks Rhinoconjunctivitis Quality of Life Questionnaire

Countries

Thailand

Contacts

Public ContactWaipoj Chanvimalueng

Department of Otolaryngology Faculty of Medicine Thammasat University

waipoj@tu.ac.th02-926-9839

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026