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Effect of single rectal dose of Misoprostol prior to abdominal hysterectomy in women with symptomatic leiomyoma: a randomized double blinded clinical trial

Effect of single rectal dose of Misoprostol prior to abdominal hysterectomy in women with symptomatic leiomyoma: a randomized double blinded clinical trial

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20150924001
Enrollment
Unknown
Registered
2015-09-24
Start date
2015-09-22
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fibroids uterine fibroma Misoprostol bleeding volume abdominal hysterectomy

Interventions

400 micrograms rectal Misoprostol was administered to cases 30 minutes prior to operation. The controls received placebo in return. The patients were hospitalized one day prior to operation. Age&#44
previous operations and BMI were registered. Total bleeding was assessed by blood volume in suction set and surgical Gauzes (15 cc for each gauze and 50 cc for each long gauze). Before&#44
8 and 30 hours following surgery&#44
Hb levels were registered.
Experimental Drug
Misoprostol

Sponsors

shahid sadoughi university of medical sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
30 Years to 80 Years

Inclusion criteria

Inclusion criteria: patients hospitalized due to uterine myoma in Gynecology ward of Shahid Sadoughi hospital in 2012, candidate for abdominal hysterectomy

Exclusion criteria

Exclusion criteria: chemoterapy

Design outcomes

Primary

MeasureTime frame
Hb levels 8 and 30 hours following surgery micro gram

Secondary

MeasureTime frame
Age, previous operations and BMI before surgery nil

Countries

iran

Contacts

Public Contactpouria yazdian

medical student, shahid sadoughi university of medical sciences, yazd, iran

pouria_yazdian_a@yahoo.com+989385101025

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026