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Comparison of Efficacy Between Thermal Pulsatile System (Lipiflow®) And Conventional Lid Hygiene In Anti-Glaucoma Agent Related Meibomian Gland Dysfunction

Comparison of Efficacy Between Thermal Pulsatile System (Lipiflow®) And Conventional Lid Hygiene In Anti-Glaucoma Agent Related Meibomian Gland Dysfunction

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20150919001
Enrollment
60
Registered
2015-09-19
Start date
2015-09-14
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

glaucoma patients Lipiflow meibomian gland dysfunction topical glaucoma medication

Interventions

Single treatment with Lipiflow instrument&#44
lid hygiene,patient performs well&#45
instructed standard lid hygiene at least once a day
Lipiflow,Lid hygiene

Sponsors

None
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age more than 18 years old 2.Prescribed with one or more topical anti-glaucoma medications in both eyes 3.Diagnosed with MGD stage II or stage III

Exclusion criteria

Exclusion criteria: 1.Blindness or have one eye 2.Underwent trabeculectomy procedure 3.Have advance glaucoma or uncontrolled IOP 4.Have history of ocular surgery or injury within prior 3 months 5.Have history of ocular herpes within prior 3 months 6.Have active ocular inflammation or infection 7.Have eyelid or ocular surface abnormalities 8.Diagnoses with systemic disease causing dry eye

Design outcomes

Primary

MeasureTime frame
meibomian gland expressibility 1 week, 1 month, 3 month, 6 month after intervention meibomian gland express score

Secondary

MeasureTime frame
Dry eye symptoms 1 week, 1 month, 3 month, 6 month after intervention interview with questionnaire OSDI score,Tear film stability 1 week, 1 month, 3 month, 6 month after intervention slit lamp examination with tear break up time test,Corneal surface 1 week, 1 month, 3 month, 6 month after intervention Slit lamp examination with corneal staining Oxford score,Tear film lipid layer thickness 1 week, 1 month, 3 month, 6 month after intervention measure with Lipiview instrument,Tear production 1 week, 1 month, 3 month, 6 month after intervention Schirmer's test,meibomian gland drop out 1 week, 1 month, 3 month, 6 month after intervention using meibography

Countries

Thailand

Contacts

Public ContactNgamjit Kasetsuwan

Chulalongkorn University

ngamjitk@gmail.com0819200553

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026