PRIMARY OPEN ANGLE GLAUCOMA WITH OR WITHOUT MYOPIA glaucoma myopia Ultra-
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Target population are divided into 4 groups 1. Myopia with POAG 2. Emmetropia with POAG 3. Myopia without glaucoma 4. Emmetropia without glaucoma Inclusion Criteria for all groups Age > 40 years POAG group Inclusion criteria - IOP ≥ 21 mmHg - Open angle on gonioscopic examination - Characteristic signs of optic disc damage (glaucomatous optic neuropathy) - Glaucomatous visual field defects on perimetry Non-glaucoma group Inclusion criteria Patients with no evidence of - Enlargement of optic disc cup: cup-to-disc (C:D) ratio > 0.5 - Focal enlargement of cup disc cup - Loss of retinal nerve fiber layer defect - Asymmetrical of cupping between the patients' eyes (difference > 0.2) - IOP elevation ≥ 21 mmHg - No family history of glaucoma Myopia group Inclusion criteria - Patients who has refractive error (spherical equivalence) ≥ -4.00 D - Patients who has axial length ≥ 26 mm. Emmetropia group Inclusion criteria - Patients who has refractive error (spherical equivalence) between -0.50 and +0.50 D - Patients who has axial length < 26 mm.
Exclusion criteria
Exclusion criteria: Exclusion Criteria for all groups - Patients with history of any other ocular pathology (except for cataract, posterior vitreous detachment, dry eye without keratitis) - Patients with any corneal pathology - Patients with history of corneal surgery e.g. pterygium excision, refractive surgery - Patients with history of cataract surgery e.g. Phacoemulsification, Extracapsular cataract extraction (ECCE), Intracapsular cataract extraction (ICCE) - Pregnancy - Patients with underlying connective tissue disease - Patients who unable to give consent - Patients who unable to perform the test POAG group Exclusion criteria Other types of glaucoma included combined mechanism of glaucoma e.g. POAG with uveitis glaucoma Non-glaucoma group Exclusion criteria Patients who have no data or unable to assess optic disc
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The deformation amplitude day 0 air puff tonometry | — |
Secondary
| Measure | Time frame |
|---|---|
| Corneal biomechanical properties day 0 air puff tonometry | — |
Contacts
King Chulalongkorn Memorial Hospital