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High-flow nasal cannula oxygen versus non-invasive ventilation in flexible bronchoscopy

A prospective randomized comparative study of high-flow nasal cannula oxygen and non-invasive ventilation in hypoxemic patients undergoing diagnostic flexible bronchoscopy

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20150828001
Enrollment
Unknown
Registered
2015-08-28
Start date
2015-09-01
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypoxemia during flexible bronchoscopy High&#45

Interventions

HFNC Setting: FiO2 0.6 Flow 40 L/min,NIV Setting: FiO2 0.6&#44
PEEP 5&#44
Inspiration pressure keeps tidal volume 8&#45
10 cc/kg or at least 10 cmH2O
Active Comparator Device,Experimental Device
High&#45
flow nasal cannula,Non&#45
invasive ventilation

Sponsors

None
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Patients with age 15 years or more who have hypoxemia defined as PaO2 less than 70 mmHg at room air who require flexible bronchoscopy for diagnosis of abnormal pulmonary lesions. 2. Patients give consent form

Exclusion criteria

Exclusion criteria: 1. Contraindications for NIV or HFNC. 2. Indications for intubation 3. Preexisting invasive ventilation 4. Refuse to participate study

Design outcomes

Primary

MeasureTime frame
oxygen saturation level During flexible bronchoscopy Pulse oximetry—

Secondary

MeasureTime frame
vital signs Before, during, and after flexible bronchoscope BP, HR, RR,arterial blood gases Before, during, and after flexible bronchoscope arterial blood gases,dyspnea score Before, during, and after flexible bronchoscope visual analog scale—

Countries

Thailand

Contacts

Public ContactViboon Boonsarngsuk

Ramathibodi Hospital, Mahidol University

bss-vb@hotmail.com6622011629

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026