Osteoarthritis Knee Total knee arthroplasty Postoperative TKA analgesia adductor canal block Total knee arthroplasty Postoperative analgesia functional outcome single shot adductor canal block local infiltration analgesia
Conditions
Interventions
0.5%levobupivacaine 20 ml+morphine 5 mg.+ adrenaline (1 : 1,
000) 0.3 ml + normal saline up to 60 ml inject at anterior,
medial,
lateral and supra-
patella pouch of the knee,
before insertion of prosthetic instruments and before suture surgical wound.,single shot adductor canal block under high frequency linear ultrasound,
by 22 gauge 100 mm. stimuplex-
0.5%levobupivacaine 20 ml was injected at recovery room.
Active Comparator Drug,Active Comparator Drug
local infiltration analgesia after total knee arthroplasty,single shot adductor canal block
Sponsors
Research Affairs Faculty of medicine, Chulalongkorn University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patient aged > 18 years old, who was scheduled for total knee arthroplasty American Society of anesthesiologist class 1-3 Patient BMI 18-40 kg/m2
Exclusion criteria
Exclusion criteria: refuse to participate this study allergy to any drug in this study age 3 BMI 40 kg/m2 contraindication to neuraxial anesthesia uncontrolled hypertension or Blood pressure greater than 140/90 mmmHg history of heart failure, cerebrovascular disease, cardiac surgery, coronary artery disease history of upper GI bleeding, gastric ulcer history of abnormal liver enzyme, hepatic failure, renal failure, organ transplantation, coagulopathy chronic opioids user defined as using opioids drug almost/everyday for three consecutive months or more than 60 mg/day for one month neuropathic pain failure to single shot adductor canal block inability to cooperate with Time Up and Go Test before surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| morphine consumption postoperative 24 hours postoperative 24 hr mg of morphine consumption using PCA device | — |
Secondary
| Measure | Time frame |
|---|---|
| degree of knee flexion(active and passive) postoperative day1,2,3 postoperative day 1, 2, 3 degree of range of motion,morphine consumption postoperative 48 hours postoperative 48 hr mg of morphine consumption using PCA device,Pain score postoperative 6,12,18 hours postoperative 6,12,18 hours visual analog scale,pain score at rest, sit, flexion, extension of the knee postoperative postoperative day 1 in the morning and evening visual analog scale,pain score at rest, sit, stand, walk postoperative postoperative day 2,3 visual analog scale,Quadriceps strength postoperative day 1, 2, 3 postoperative day 1, 2, 3 maximum voluntary isometric contraction,rehabilitation after surgery on postoperative day 3 The Timed Up and Go test (TUG),pain score postoperative 2,6,12 weeks postoperative 2,6,12 weeks visual analog scale,rehabilitation after surgery postoperative 2,6,12 weeks The Timed Up and Go test (TUG) | — |
Countries
Thailand
Contacts
Public ContactWireena Kampitak
unaffiliated
Outcome results
None listed