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Neonatal effects after vasopressor during spinal anesthesia for cesarean section: a multicenter, randomized controlled trial

Neonatal effects after vasopressor during spinal anesthesia for cesarean section

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20150609004
Enrollment
300
Registered
2015-06-09
Start date
2016-01-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypotension during spinal anesthesia for cesarean section ephedrine phenylephrine spinal anesthesia cesarean section

Interventions

if systolic blood pressure less than 80% of baseline &#44
given ephedrine 6 mg intravenous bolus ,if systolic blood pressure less than 80% of baseline &#44
given phenylephrine 100 mcg intravenous
Experimental Drug,Experimental Drug
ephedrine,phenylephrine

Sponsors

Ratchadapiseksompotch Fund, Faculty of Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: ASA I,II more than 18 years old Normal singleton baby GA 37-42 weeks Adequate spinal anesthesia for cesarean delivery and SBP< 80% of baseline SBP at ward

Exclusion criteria

Exclusion criteria: PIH, Preexisting hypertension Complicated obstetrics (eg.Abruptio placenta, placenta previa) Substance abuse in pregnancy 24 hr. preop. administration of pseudoephedrine, nasal decongestants, pethidine, terbutaline Known fetal abnormalities (IUGR, fetal cardiac disease)

Design outcomes

Primary

MeasureTime frame
neonatal heart rate at 30 minutes post-delivery beat per minute

Secondary

MeasureTime frame
neonatal blood pressure, respiratory rate, temperature, sugar, lactate, Apgar score at 30 minutes post-delivery mmHg, per miute, degree celcius, mg/l, mmol/l, score

Countries

Thailand

Contacts

Public ContactKetchada Uerpairojkit

faculty of medicine, Chulalongkorn university

ketchada_cc@hotmail.com66896644730

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026