Intracervical lidocaine gel for pain relief during endometrial biopsy: A double-blind randomized controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20150521002

Enrollment

130

Registered

2015-05-21

Start date

2015-06-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain control in endometrial biopsy procedure Endometrial biopsy Pain control

Interventions

Intracervical lidocaine gel with Oral paracetamol 500 mg plus Ibruprofen 400 mg before procedure 30 min,Intracervical water based&#45

soluble gel (KY gel) with Oral paracetamol 500 mg plus Ibruprofen 400 mg before procedure 30 min

Active Comparator Drug,Placebo Comparator Drug

Intracervical lidocain gel plus oral paracetamol and ibruprofen,Intracervical KY gel plus oral paracetamol and ibruprofen

Eligibility

Sex/Gender

Female

Age

35 Years to 100 Years

Inclusion criteria

Inclusion criteria: Woman over 35 year of age,who have indicate for endometrial biopsy in Songkhlanakarin hospital

Exclusion criteria

Exclusion criteria: 1. Allergy to lidocain,paracetamol or ibruprofen 2. Pregnant woman 3. Woman who have PID or STDs 4. Abnormal coagulogram 5. Unstable hemodynamic status

Design outcomes

Primary

Measure	Time frame
Efficacy of intracervical lidocaine gel during endometrial biopsy compair with placebo During endometiral biopsy (cerivcal pass and vacuum aspiration) visual analog scale	—

Secondary

Measure	Time frame
side effect of intracervical lidocaine gel after procedure Observed, physical examination	—

Countries

Thailand

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026

Intracervical lidocaine gel for pain relief during endometrial biopsy: A double&#45;blind randomized controlled trial