hypercholesterolemia Phytosterol,
Conditions
Interventions
phytosterols and inulin enriched soymilk,standard soymilk
subjects had to consume phytosterol and inulin-
enriched soymilk contained 1 g of phytosterols and 5 g of inulin twice daily for 8 weeks,subjects had to consume standard soymilk twice daily for 8 weeks
Experimental Dietary Supplement,Placebo Comparator Dietary Supplement
Sponsors
Dairy Plus Company Limited.
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1) subjects who were 18 years old or older 2) subjects who had never used statin or were taking a stable dose of statin for at least 3 months and whose LDL-c levels were 130 mg/dl or higher
Exclusion criteria
Exclusion criteria: 1) subjects who had established cardiovascular disease, 2) subjects who had any type of diabetes mellitus, 3) subjects who had gastrointestinal dysmotility, 4) subjects who had abnormal gastrointestinal digestion or absorption, 5) subjects who had an allergy to soymilk 6) subjects who had secondary hyperlipidemia such as hypothyroidism, nephrotic syndrome or hepatic disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the LDL-c levels before and after consumption of the phytosterol and inulin enriched soymilk 8 weeks enzymatic in vitro assay for direct determination using a MODULAR P800 analyzer,the LDL-c levels in the study group and the control group 8 weeks enzymatic in vitro assay for direct determination using a MODULAR P800 analyzer | — |
Secondary
| Measure | Time frame |
|---|---|
| total cholesterol, triglyceride and HDL-c levels in the study groups and control groups 8 weeks enzymatic in vitro assay for direct determination using a MODULAR P800 analyzer,adverse event rate in the study group and control group every visit (2 weeks) questionnaire, fasting plasma glucose, liver function test | — |
Countries
Thailand
Contacts
Public ContactNoppadol Kietsiriroje
faculty of medicine, Prince of Songkla University
Outcome results
None listed