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The safety and result of intratumoral steroid injection for aggressive fibromatosis

The safety and result of intratumoral steroid injection for aggressive fibromatosis

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20150409001
Enrollment
10
Registered
2015-04-09
Start date
2015-01-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

1. Procedure complications 2. Complications due to the steroid use

Interventions

1. Patients will be admitted to Chiang Mai University Hospital as one day surgery. 2. The spinal needle will be placed along the previous surgical scar or the expected future resection line of recurre
The tumor is progressive following the definition of “Progressed disease” &#45
Local complications which determined as major complications
Experimental Drug

Sponsors

Faculty of medicine, Chiang mai University
Lead Sponsor
Faculty of medicine&#44
Collaborator
Chiang mai University
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients who have been diagnosed AF by MSK-Oncology Board (MSK-OB) of Chiang Mai University and give consent to participate in this research, and 2. The disease has recurred at least one episode and progressed after the wide resection had been performed, and - Patients have experience of constant pain and not response to conservative treatment, or - The primary lesion shows locally aggressive by involving large area of normal tissue (comparing to previous MRI), and the operation is expected to create unacceptable morbidity.

Exclusion criteria

Exclusion criteria: 1. Patients who have bleeding tendency 2. Patients who depended on systemic steroid use by other conditions 3. Patients who have contra-indication for steroid use including poor control diabetes, active infection, pregnancy and lactation.

Design outcomes

Primary

MeasureTime frame
Safety for intratumoral steroid injection 6 months local of intratumoral injection and systemic and local steroid complications

Secondary

MeasureTime frame
outcome of treatment 6 months pain score, functional score and tumor volume

Countries

Thailand

Contacts

Public Contactdumnoensun pruksakorn

Chiang Mai University

dumnoensun@hotmail.com0882614773

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026