Efficacy of non-invasive ventilation versus standard oxygen therapy in emergency patients with respiratory distress: A randomized controlled trial

Efficacy of non-invasive ventilation versus standard oxygen therapy in emergency patients with respiratory distress: A randomized controlled trial.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20150325002

Enrollment

Unknown

Registered

2015-03-25

Start date

2014-05-01

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

respiratory distress&#44

Interventions

standard oxygen thearpy via oxygen cannula or rebreathing mask for 2 hours,non&#45

invasive ventilation via oro&#45

nasal mask for 2 hours

Active Comparator Device,Experimental Device

standard oxygen therapy,non&#45

invasive ventilation

Eligibility

Sex/Gender

All

Age

0 Years to 0 Years

Inclusion criteria

Inclusion criteria: age more than 18 years respiratory rate more than 24 breath per minuts use of accessory muscle or abdominal paradox room air oxygen saturation below 95 %

Exclusion criteria

Exclusion criteria: Cardiac arrest Unstable medical condition e.g. shock myocardial infarction Respiratory failure defined by respiratory rate > 35 breath per minutes and oxygen saturation < 90% after oxygen theary High risk for aspiration Large amount of secretion Glasgow coma scale < 13 unco-operated patients untreated pneumothorax recent airway or upper GI tract or esophageal surgery unfit mask pregnancy required immediate intubation

Design outcomes

Primary

Measure	Time frame
respiratory rate 120 minutes breaths per minute	—

Secondary

Measure	Time frame
respiratory rate 60 minutes breaths per minute,pulse rate 120 minutes beats per minute,intubation rate within 24 hours percentage,mortality rate within 7 days percentage,hospital length of stay no days,complication of non-invasive ventilation no percentage,success rate of non-invasive ventilation no percentage	—

Countries

Thailand

Contacts

Public ContactNattakarn Praphruetkit

Faculty of Medicine, Siriraj Hospital, Mahidol University

nattakarn107@yahoo.com024199216

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026

Efficacy of non&#45;invasive ventilation versus standard oxygen therapy in emergency patients with respiratory distress: A randomized controlled trial