-
Conditions
Interventions
patients in Placebo group had recieved normal saline 2 ml
Experimental Drug,Placebo Comparator Drug
Ketamine group,Placebo group
20 minutes before the operation finished,
patients in Ketamine group had recieved ketamine 0.25 mg/kg
,20 minutes before the operation finished,
Sponsors
Faculty of Medicine, Prince of Songkla University
Faculty of Medicine,
Prince of Songkla University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: - age 18-65 years - ASA clasiification I-III - undergo general anesthesia with orthopedics surgery - duration of surgery 1-3 hours
Exclusion criteria
Exclusion criteria: - no inform consent - ketamine allergy - BMI > 35 kg/m2 - preoperative core temperature > 38 c or < 35 c - hypo-hyperthyroidism - Parkinson's disease - requiring blood transfusion during surgery - severe cardiopulmonary disease - neuromuscular disease - history of convulsion - pregnancy - not pass reocery room - plan post operative on respirator or ICU - intake tramadol or clonidine before surgery - receive ondansetron - psychiatric disorder (Schizophrenia)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of shivering in recovery room 30 minutes observe shivering follow by Crossley and Mahajan scale | — |
Secondary
| Measure | Time frame |
|---|---|
| side effect of ketamine 30 minutes observe clinical presentation | — |
Countries
Thailand
Contacts
Public ContactSuttasinee Petskul
Department of Anesthesiology, Faculty of Medicine, Prince of Songkla University
Outcome results
None listed