Blood Pressure Lowering and Platelet Inhibitory Effects of Juices from Pachyrhizus erosus L. root and Psidium guajava L. fruit: a Control Study in Healthy Volunteers.

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

TCTR

Registry ID

TCTR20150228001

Enrollment

Unknown

Registered

2015-02-28

Start date

2011-03-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular problems including hypertension and platelet hyperactivity. Yam been root juice Guava fruit juice Circulating nitrate Circulating nitrite Blood pressure lowering effect Platelet inhibitory effect Plasma cGMP

Interventions

Nitrate&#45

free water,Yam bean root juice,Guava fruit juice

Placebo Comparator No treatment,Experimental Dietary Supplement,Experimental Dietary Supplement

Control treatment,Yam bean root juice,Guava fruit juice

Eligibility

Sex/Gender

All

Age

20 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Age between 20 to 45 years. 2. Body mass index (BMI) of 18-27 kg per square meter.

Exclusion criteria

Exclusion criteria: 1. History of any serious illnesses, including infectious diseases, cardiovascular and pulmonary diseases. 2. Smoking and/or alcoholic drinking. 3. Systemic medication (other than the oral contraceptive pill). 4. Pregnancy.

Design outcomes

Primary

Measure	Time frame
Blood pressure and heart rate 0, 0.5, 1, 1.5, 2, 2.5, 3, 5 hours Blood pressure and heart rate monitoring	—

Secondary

Measure	Time frame
Platelet function 0, 2.5, 5 ours Platelet aggregation assessment	—

Countries

Thailand

Contacts

Public ContactSupeenun Unchern

Lecturer/Investigator

supeenun.unc@mahidol.ac.th662-2015641

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026