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Premedication with oral paracetamol for reduction of propofol injection pain

Premedication with oral paracetamol for reduction of propofol injection pain

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20150224002
Enrollment
324
Registered
2015-02-24
Start date
2015-06-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

propofol injection pain Propofol Propofol injection pain Paracetamol

Interventions

Paracetamol 500 mg,Paracetamol 1000 mg,Placebo
Patient received Paracetamol 500 mg 1 hr before the operation,Patient received Paracetamol 1000 mg 1 hr before the operation,Patient received Placebo 1 hr before the operation

Sponsors

Faculty of Medicine Prince of Songkla University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: ASA class I-III Elective surgery with general anesthesia IV insertion at dorsum of hand

Exclusion criteria

Exclusion criteria: Difficulty in communication BW below 50 kgs Patuents who have Hypertension, Cardiovascular disease Renal failure or CrCl ≤ 10 Hepatic failure or transminitis Allergy to paracetamol or propofol Infection on the dorsum of hand Patients who need a Rapid sequence induction for intubation Patients who refuse to join the study

Design outcomes

Primary

MeasureTime frame
Severity of pain during propofol injection pre-post Verbal numerical rating score

Secondary

MeasureTime frame
The proper dose of oral paracetamol for reduction propofol injection pain pre-post Verbal numerical rating score

Contacts

Public ContactSasikaan Nimmaanrat

Prince of Songkla university

snimmaanrat@yahoo.com.au0887907842

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026