Platelet aggregation Thai traditional medicine complimentary and alternative medicine Siriraj Ayurved recipe (AVS022) platelet aggregation adrenaline ADP collagen
Conditions
Interventions
1500 mg oral every 8 hours for total 3 doses,oral route every 8 hours for 3 times
Active Comparator Other,Placebo Comparator Other
AVS022,Placebo
Sponsors
Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand
Thailand Research Fund (TRF)
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Male and female age between 18 and 45 years, considered healthy based on medical history, physical examination and laboratory test (hematology, blood biochemistry, lipid profiles, urine analysis and urine pregnancy test in only female volunteers).
Exclusion criteria
Exclusion criteria: Subject who takes drugs that affect platelet function such as aspirin,clopidogrel, etc. or has a history of drug allergy especially antipyretic drug including paracetamol or Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) or participated in other research less than 1 month from the enrollment date.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Platelet aggregation before dose and at 8, 32 hours and 7-10 days after the first dose the percentage of platelet aggregation | — |
Secondary
| Measure | Time frame |
|---|---|
| AVS022 safety after dosing until 7-10 days after dose rate and type of adverse events | — |
Countries
Thailand
Contacts
Public ContactWeerawadee Chandranipapongse
Faculty of Medicine Siriraj Hospital, Mahidol University
Outcome results
None listed