Intraoperative hypothermia Blood pressure Intraoperative hypothermia Ephedrine Propofol Temperature
Conditions
Interventions
Mixture of 12 mg of ephedrine (6mg/ml) and propofol for induction of general anesthesia,Mixture of 2 ml of normal saline and propofol for induction of general anesthesia
Experimental Drug,Placebo Comparator Drug
Ephedrine,Normal saline
Sponsors
None
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Thirty patients with age of 18-70 years old and American society of anesthesiologist physical status I-III who were scheduled to undergo plastic or breast surgery with expected duration of surgery longer than 120 minutes in Ramathibodi hospital.
Exclusion criteria
Exclusion criteria: Tympanic temperature more than 37.5 Blood pressure at time of induction more than 140/90 mmHg BMI more than 30 Thyroid disease Hypertension receiving medications Risk of aspiration or expected difficult airway Actual surgery time less than 90 minutes Hand, wrist, forearm or intraoral surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Esophageal temperature difference between group 120 minutes Esophageal temperature in Celcius | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure difference between group 120 minutes NIBP in mmHg | — |
Countries
Thailand
Contacts
Public ContactThanist Pravitharangul
Faculty of Medicine, Ramathibodi hospital
Outcome results
None listed