Zinc supplement in acute asthma exacerbations

Efficacy of zinc supplemenatation for the treatment of acute exacerbations of asthma in children: A randomized, double-blind, placebo-control trial

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20141212001

Enrollment

Registered

2014-12-12

Start date

2015-01-01

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute asthmatic attack Asthma Zinc

Interventions

Subjects in this group will take chelated zinc (15 mg element zinc) daily during admission in the hospital.,Subjects will take placebo which has same form of the active group&#44

once daily during admission.

Active Comparator Dietary Supplement,Placebo Comparator No treatment

Zinc,Placebo

Eligibility

Sex/Gender

All

Age

1 Years to 15 Years

Inclusion criteria

Inclusion criteria: Children admitted to the hospital due to acute asthma exacerbattions

Exclusion criteria

Exclusion criteria: bronchopulmenary dysplasia congenital heart diseases chronic renal failure

Design outcomes

Primary

Measure	Time frame
asthma severity 4 days after intervention Pediatric Respiratory Assessment Measure (PRAM) score	—

Secondary

Measure	Time frame
Zinc levels at the end of study serum zinc levels	—

Countries

Thailand

Contacts

Public ContactSanguansak Rerksuppaphol

Srinakharinwirot University

sanguansak_r@hotmail.com0817231766

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026