advert event from antibiotic Pre-
Conditions
Interventions
tailored triple therapy alone (esomeprazole 20 mg bid,
clarithromycin 500 mg bid or metronidazole 400 mg tid if clarithromycin resistance and amoxicillin 1000 mg bid) ,tailored triple therapy plus pre-
treatment with probiotics containing Lactobacillus delbrueckii subp. bullgaricus and Streptococcus thermophillus
No Intervention Drug,Experimental Dietary Supplement
tailored triple therapy alone,tailored triple therapy plus probiotic
Sponsors
Suranaree University of Technology
SUT HOSPITAL
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Helicobacter pylori associated gastritis patients
Exclusion criteria
Exclusion criteria: age below 18 or above 70 years, previous Helicobacter pylori eradication treatment before previous 2 months, gastric ulcer or duodenal ulcer, suspected or confirmed malignancy on endoscopy, significant medical illnesses and history of previous gastric surgery, pregnant or lactating women, and the use of antimicrobials or gastrointestinal medications like PPIs or bismuth compounds within the previous 2 months, refuse yogurt due to underlying disease such as DM ,history of drug allergy in first line therapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pre-treatment with probiotics on tailored triple therapy can improve Helicobacter Pylori eradication 1 month Eradication rate between two group | — |
Secondary
| Measure | Time frame |
|---|---|
| advert event 1 month rate of advert event between two group | — |
Countries
Thailand
Contacts
Public Contacttaweesak tongtawee
department of surgery
Outcome results
None listed