Efficacy of EPA-enriched supplement compared with standard formula on body weight changing in malnourished head and neck cancer patients undergone surgery : A randomized study

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20141204002

Enrollment

Registered

2014-12-04

Start date

2014-11-24

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malnourished head and neck cancer patients undergone surgery Malnourished Head and Neck Cancer Surgery

Interventions

EPA&#45

enriched supplement is given to the patients for 3 weeks (1 week prior to surgery and 2 weeks post surgery). The supplement composes of 2.2 gm of EPA and 630 kcal daily.,The standard formula supplemen

Experimental Dietary Supplement,No Intervention Dietary Supplement

enriched supplement,standard formula supplement

Eligibility

Sex/Gender

All

Age

15 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed as Head an Neck cancer with pathological confirmation 2. Receiving surgery as a primary treatment 3. Malnutrition screening tool(MST) is 2 or more

Exclusion criteria

Exclusion criteria: 1. Previously irradiated patient in the Head and Neck region 2. Previously receiving chemotherapy 3. Renal insufficiency with serum creatinine > 2.5 mg/dL 4. Liver function abnormality with total serum bilirubin > 3.0 mg/dL 5. Pregnancy

Design outcomes

Primary

Measure	Time frame
ÚBody weight 1week prior intervention; 3 weeks, 1 month, 3 months post intervention kilogram	—

Secondary

Measure	Time frame
Bioelectrical Impedance Analysis (BIA) 1week prior intervention; 3 weeks, 1 month, 3 months post intervention percent	—

Countries

Thailand

Contacts

Public ContactKitti Jantharapattana

Faculty of Medicine, Prince of Songkla University

kittient@hotmail.com(66)074451390

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026

Efficacy of EPA&#45;enriched supplement compared with standard formula on body weight changing in malnourished head and neck cancer patients undergone surgery : A randomized study